Across TCGA patient cohorts, ZNF652 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF652-associated genes across cancer lineages are eEF2, Rad50, and EGFR_pY1068. Each is linked with ZNF652 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF652-to-partner and partner-to-ZNF652 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF652→partner) and Y-score (partner→ZNF652) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.302	+1.353	.007	.015	3	2
UCEC	Rad50 →	-0.225	-1.353	.003	.015	3	2
UCEC	EGFR_pY1068 →	-0.277	-1.836	<.001	.001	3	1
UCEC	eIF4E →	+0.220	+2.115	<.001	<.001	2	2
UCEC	eIF4G →	+0.332	+2.999	<.001	<.001	3	1
UCEC	A-Raf_pS299 →	-0.155	-2.169	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

ZNF652 survival (RNA) · tumor vs normal (RNA) · all ZNF652 data types