Across TCGA cell cohorts, ZNF652 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF652-associated genes across cancer lineages are PI3Ka_4409, GSK2276186C, and 123829. Each is linked with ZNF652 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF652-to-partner and partner-to-ZNF652 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF652→partner) and Y-score (partner→ZNF652) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PI3Ka_4409 →	-0.392	-2.743	.028	.046	3	1
LARGE_INTESTINE	GSK2276186C →	+0.447	+2.871	.042	.021	3	1
LARGE_INTESTINE	123829 →	+0.658	+2.871	.016	.021	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.694	+2.868	.002	.022	3	1
LARGE_INTESTINE	AR-42 →	-0.585	-2.736	.013	.044	3	1
LARGE_INTESTINE	Belinostat →	-0.439	-2.595	.041	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ZNF652 survival (RNA) · tumor vs normal (RNA) · all ZNF652 data types