ZNF646

Across TCGA patient cohorts, ZNF646 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,582 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF646-associated proteins across cancer lineages are CD2BP2, DCTPP1, and GTF3C1. Each is linked with ZNF646 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF646-to-partner and partner-to-ZNF646 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF646 versus CD2BP2 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF646→partner) and Y-score (partner→ZNF646) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CD2BP2 →	+0.267	+0.420	<.001	<.001	3	6
LSCC	DCTPP1 →	+0.546	+0.419	<.001	<.001	3	5
LSCC	GTF3C1 →	+0.251	+0.386	<.001	<.001	3	5
LSCC	GTF3C2 →	+0.216	+0.333	<.001	<.001	3	5
COAD	USP7 →	+0.268	+0.485	<.001	<.001	3	5
GBM	CXXC1 →	+0.188	+0.254	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,582 associations by consensus.

ZNF646 vs CD2BP2 — LSCC

Explore this scatter interactively →