ZNF646

Across TCGA patient cohorts, ZNF646 protein abundance is significantly associated with the RNA expression of many other genes, with 5,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF646-associated genes across cancer lineages are GBAP1, RECQL5, and TSEN54. Each is linked with ZNF646 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF646-to-partner and partner-to-ZNF646 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF646 versus GBAP1 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF646→partner) and Y-score (partner→ZNF646) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GBAP1 →	+0.948	+0.486	.002	.003	3	3
UCEC	RECQL5 →	+0.768	+0.428	.003	.002	3	3
UCEC	TSEN54 →	+1.074	+0.508	<.001	<.001	3	3
BRCA	FBF1 →	+0.787	+0.609	.002	<.001	3	3
OV	HMCN1 →	-1.290	-1.744	.006	.003	3	3
CCRCC	ACTR5 →	+0.365	+0.507	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,170 associations by consensus.

ZNF646 vs GBAP1 — BRCA

Explore this scatter interactively →