ZNF644

Across TCGA patient cohorts, ZNF644 mutation is significantly associated with the RNA expression of many other genes, with 3,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF644-associated genes across cancer lineages are TYMS, CDC7, and RNA5SP412. Each is linked with ZNF644 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF644-to-partner and partner-to-ZNF644 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TYMS grouped by ZNF644-low versus ZNF644-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF644→partner) and Y-score (partner→ZNF644) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TYMS →	+0.690	+1.847	<.001	<.001	3	4
UCEC	CDC7 →	+0.598	+2.595	<.001	<.001	3	4
UCEC	RNA5SP412 →	+0.463	+1.464	<.001	.002	3	3
LIHC	LINC01817 →	+0.070	+3.964	.001	.005	3	3
UCEC	CDKN3 →	+0.599	+1.513	<.001	<.001	3	3
UCEC	RBFA →	+0.293	+1.531	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,847 associations by consensus.

TYMS by ZNF644 expression — UCEC

Explore this box plot interactively →