ZNF644

Across TCGA cell cohorts, ZNF644 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,865 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF644-associated GO terms across cancer lineages are Positive regulation of centriole replication, Positive regulation of organelle assembly, and Regulation of centrosome duplication. Each is linked with ZNF644 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF644-to-partner and partner-to-ZNF644 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of centriole replication grouped by ZNF644-low versus ZNF644-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF644→partner) and Y-score (partner→ZNF644) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of centriole replication →	+0.124	+0.794	<.001	<.001	3	17
STOMACH	Positive regulation of organelle assembly →	+0.082	+0.977	<.001	<.001	3	15
LUNG_SCLC	Regulation of centrosome duplication →	+0.103	+0.639	<.001	<.001	3	14
STOMACH	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.246	+0.807	.001	.001	3	13
KIDNEY	Zinc ion import into Golgi lumen →	+0.098	+0.511	.004	.007	2	14
STOMACH	Regulation of termination of RNA polymerase II transcription →	+0.167	+0.971	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,865 associations by consensus.

Positive regulation of centriole replication by ZNF644 expression — LUNG_SCLC

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