ZNF644

Across TCGA cell cohorts, ZNF644 mutation is significantly associated with the RNA expression of many other genes, with 162 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF644-associated genes across cancer lineages are TMEM215, KRTAP4-4, and PRB1. Each is linked with ZNF644 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF644-to-partner and partner-to-ZNF644 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM215 grouped by ZNF644-low versus ZNF644-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF644→partner) and Y-score (partner→ZNF644) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TMEM215 →	+0.244	+4.786	<.001	.001	3	2
BLOOD_Lymphoma	KRTAP4-4 →	+0.016	+4.643	<.001	.005	3	2
BLOOD_Lymphoma	PRB1 →	+0.052	+4.350	<.001	.005	3	2
LARGE_INTESTINE	RSPH6A →	+0.085	+3.051	.005	<.001	3	2
CNS	OR52K2 →	+0.065	+3.772	<.001	.008	3	2
CNS	KRT77 →	+0.034	+3.981	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 162 associations by consensus.

TMEM215 by ZNF644 expression — PANCREAS

Explore this box plot interactively →