ZNF641

Across TCGA patient cohorts, ZNF641 mutation is significantly associated with the RNA expression of many other genes, with 1,216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF641-associated genes across cancer lineages are MIR8082, CRY1, and RN7SL252P. Each is linked with ZNF641 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF641-to-partner and partner-to-ZNF641 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8082 grouped by ZNF641-low versus ZNF641-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF641→partner) and Y-score (partner→ZNF641) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8082 →	+0.362	+2.462	<.001	<.001	3	2
UCEC	CRY1 →	+0.614	+2.180	<.001	.002	3	2
UCEC	RN7SL252P →	+0.105	+2.184	.005	.004	3	2
BLCA	LINC02619 →	+0.083	+4.588	<.001	.008	3	2
UCEC	POMP →	+0.424	+2.684	.002	<.001	3	2
UCEC	BORA →	+0.575	+2.180	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,216 associations by consensus.

MIR8082 by ZNF641 expression — UCEC

Explore this box plot interactively →