ZNF641

Across TCGA patient cohorts, ZNF641 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF641-associated genes across cancer lineages are Epithelial cells, Keratinocytes, and Class-switched memory B-cells. Each is linked with ZNF641 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF641-to-partner and partner-to-ZNF641 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by ZNF641-low versus ZNF641-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF641→partner) and Y-score (partner→ZNF641) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.083	-2.107	.002	.018	3	2
UCEC	Keratinocytes →	-0.011	-2.837	.038	.038	3	2
UCEC	Class-switched memory B-cells →	-0.056	-2.809	.008	.001	3	1
UCEC	CLP →	-0.052	-3.138	.028	.019	3	1
UCEC	Macrophages M2 →	+0.009	+1.883	.016	.007	3	1
UCEC	MEP →	+0.022	+2.254	.033	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Epithelial cells by ZNF641 expression — UCEC

Explore this box plot interactively →