ZNF641

Across TCGA cell cohorts, ZNF641 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF641-associated genes across cancer lineages are UNC13C, SULT6B1, and HCN4. Each is linked with ZNF641 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF641-to-partner and partner-to-ZNF641 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNC13C grouped by ZNF641-low versus ZNF641-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF641→partner) and Y-score (partner→ZNF641) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UNC13C →	+0.443	+3.691	<.001	.009	3	1
LARGE_INTESTINE	SULT6B1 →	+0.032	+3.977	<.001	.001	3	1
LARGE_INTESTINE	HCN4 →	+0.177	+3.415	<.001	.009	3	1
LARGE_INTESTINE	HSF5 →	+0.057	+4.321	<.001	<.001	3	1
LARGE_INTESTINE	NCR1 →	+0.119	+3.841	.001	.003	3	1
LARGE_INTESTINE	PRAMEF33 →	+0.076	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

UNC13C by ZNF641 expression — LARGE_INTESTINE

Explore this box plot interactively →