ZNF639

Across TCGA patient cohorts, ZNF639 mutation is significantly associated with the RNA expression of many other genes, with 742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF639-associated genes across cancer lineages are RN7SL470P, RNA5SP251, and TRAJ39. Each is linked with ZNF639 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF639-to-partner and partner-to-ZNF639 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL470P grouped by ZNF639-low versus ZNF639-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF639→partner) and Y-score (partner→ZNF639) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL470P →	+0.259	+3.754	<.001	.008	3	3
HNSC	RNA5SP251 →	+0.273	+5.578	.001	.004	3	2
LUSC	TRAJ39 →	+0.849	+2.869	.002	.009	3	2
LUSC	RNU7-95P →	+0.299	+4.517	<.001	.004	3	2
LUSC	RN7SL567P →	+0.145	+3.356	<.001	.007	3	2
BLCA	USP21P2 →	+0.061	+4.497	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

RN7SL470P by ZNF639 expression — LUAD

Explore this box plot interactively →