Across TCGA cell cohorts, ZNF628 mutation is significantly associated with the RNA expression of many other genes, with 194 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF628-associated genes across cancer lineages are IFNA13, CDC40, and HR. Each is linked with ZNF628 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF628-to-partner and partner-to-ZNF628 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF628→partner) and Y-score (partner→ZNF628) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	IFNA13 →	+0.043	+5.169	<.001	.004	3	2
BLOOD_Leukemia	CDC40 →	+0.509	+3.489	.008	.001	3	2
BLOOD_Leukemia	HR →	+1.053	+3.455	<.001	.002	3	2
BLOOD_Leukemia	KHDC3L →	+0.093	+2.359	.004	.007	3	2
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.000	<.001	.003	3	2
LARGE_INTESTINE	CCDC25 →	+0.578	+3.451	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 194 associations by consensus.

Exploration

ZNF628 survival (RNA) · tumor vs normal (RNA) · all ZNF628 data types