ZNF622

Across TCGA patient cohorts, ZNF622 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,800 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF622-associated proteins across cancer lineages are OTULIN, TARS1, and TRIO. Each is linked with ZNF622 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF622-to-partner and partner-to-ZNF622 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF622 versus OTULIN in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF622→partner) and Y-score (partner→ZNF622) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OTULIN →	+0.236	+0.434	.005	.001	2	6
LSCC	TARS1 →	+0.386	+0.583	<.001	<.001	3	5
LSCC	TRIO →	+0.330	+0.447	<.001	<.001	3	4
LSCC	HMGCS1 →	+0.702	+0.441	<.001	.001	3	4
OV	CCDC6 →	+0.401	+0.306	<.001	.002	3	4
BRCA	PDCD6 →	+0.283	+0.410	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,800 associations by consensus.

ZNF622 vs OTULIN — OV

Explore this scatter interactively →