ZNF622

Across TCGA patient cohorts, ZNF622 protein abundance is significantly associated with the RNA expression of many other genes, with 14,673 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF622-associated genes across cancer lineages are ITGA9, EEF1AKMT4, and NDUFS6. Each is linked with ZNF622 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF622-to-partner and partner-to-ZNF622 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF622 versus ITGA9 in UCEC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF622→partner) and Y-score (partner→ZNF622) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITGA9 →	-0.930	-0.243	.001	.005	3	6
UCEC	EEF1AKMT4 →	+0.924	+0.271	.001	.002	3	6
LSCC	NDUFS6 →	+0.637	+0.398	<.001	<.001	3	6
LSCC	CCT5 →	+0.692	+0.417	<.001	<.001	3	6
CCRCC	PTH1R →	-0.932	-0.233	<.001	<.001	3	6
BRCA	ARHGEF6 →	-0.794	-0.260	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,673 associations by consensus.

ZNF622 vs ITGA9 — UCEC

Explore this scatter interactively →