ZNF622

Across TCGA patient cohorts, ZNF622 mutation is significantly associated with the RNA expression of many other genes, with 2,328 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF622-associated genes across cancer lineages are BTBD10, IMMP1L, and VTI1A. Each is linked with ZNF622 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF622-to-partner and partner-to-ZNF622 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD10 grouped by ZNF622-low versus ZNF622-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF622→partner) and Y-score (partner→ZNF622) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BTBD10 →	+0.431	+2.364	.003	<.001	3	2
UCEC	IMMP1L →	+0.425	+3.032	<.001	<.001	3	2
UCEC	VTI1A →	+0.368	+2.828	.001	<.001	3	2
UCEC	GPATCH11 →	+0.380	+2.850	.005	.001	3	2
UCEC	BUB3 →	+0.542	+3.981	<.001	<.001	3	2
UCEC	RMND1 →	+0.583	+2.447	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,328 associations by consensus.

BTBD10 by ZNF622 expression — UCEC

Explore this box plot interactively →