ZNF622

Across TCGA cell cohorts, ZNF622 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,345 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF622-associated GO terms across cancer lineages are Ribosome hibernation, Response to rapamycin, and Cellular response to rapamycin. Each is linked with ZNF622 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF622-to-partner and partner-to-ZNF622 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome hibernation grouped by ZNF622-low versus ZNF622-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF622→partner) and Y-score (partner→ZNF622) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ribosome hibernation →	+0.161	+1.062	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Response to rapamycin →	+0.105	+1.040	.002	<.001	3	13
OESOPHAGUS	Cellular response to rapamycin →	+0.183	+0.998	.004	<.001	3	11
BREAST	Thalamus development →	+0.230	+0.961	<.001	<.001	3	10
KIDNEY	Response to mitochondrial depolarisation →	+0.096	+0.636	.008	<.001	3	10
BONE	Exocyst localization →	+0.281	+0.687	<.001	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,345 associations by consensus.

Ribosome hibernation by ZNF622 expression — UPPER_AERODIGESTIVE_TRACT

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