ZNF621

Across TCGA patient cohorts, ZNF621 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,858 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF621-associated proteins across cancer lineages are KIAA1143, RBM15B, and TOP2B. Each is linked with ZNF621 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF621-to-partner and partner-to-ZNF621 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF621 versus KIAA1143 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF621→partner) and Y-score (partner→ZNF621) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIAA1143 →	+0.323	+0.511	.003	<.001	3	5
UCEC	RBM15B →	+0.229	+0.418	<.001	<.001	3	5
HNSC	TOP2B →	+0.429	+0.650	<.001	<.001	3	5
HNSC	HNRNPLL →	+0.308	+0.764	<.001	<.001	3	4
PDAC	AAAS_S495 →	+1.102	+0.297	<.001	<.001	3	4
LSCC	FKBP11 →	-0.512	-0.387	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,858 associations by consensus.

ZNF621 vs KIAA1143 — BRCA

Explore this scatter interactively →