ZNF599

Across TCGA cell cohorts, ZNF599 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,419 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF599-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNF599 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF599-to-partner and partner-to-ZNF599 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by ZNF599-low versus ZNF599-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF599→partner) and Y-score (partner→ZNF599) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.105	+0.672	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.112	+0.903	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.087	+0.806	.001	<.001	3	15
SOFT_TISSUE	ATP metabolic process →	+0.080	+0.532	<.001	<.001	3	14
PANCREAS	Protein polyubiquitination →	+0.042	+0.970	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.100	+0.878	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,419 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by ZNF599 expression — SKIN

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