ZNF598

Across TCGA patient cohorts, ZNF598 protein abundance is significantly associated with the RNA expression of many other genes, with 9,862 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF598-associated genes across cancer lineages are KCTD5, MRPS34, and DNAJA3. Each is linked with ZNF598 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF598-to-partner and partner-to-ZNF598 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF598 versus KCTD5 in COAD, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF598→partner) and Y-score (partner→ZNF598) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KCTD5 →	+0.564	+0.321	<.001	<.001	3	6
OV	MRPS34 →	+0.761	+0.473	<.001	<.001	3	6
OV	DNAJA3 →	+0.575	+0.372	<.001	<.001	3	5
OV	TRAP1 →	+0.675	+0.488	<.001	<.001	3	5
LSCC	AUNIP →	+0.713	+0.176	<.001	.001	3	5
OV	TRAF7 →	+0.634	+0.289	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,862 associations by consensus.

ZNF598 vs KCTD5 — COAD

Explore this scatter interactively →