ZNF598

Across TCGA patient cohorts, ZNF598 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,890 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF598-associated proteins across cancer lineages are GSPT1, SRRM2, and ATXN2L. Each is linked with ZNF598 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF598-to-partner and partner-to-ZNF598 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF598 versus GSPT1 in COAD, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF598→partner) and Y-score (partner→ZNF598) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GSPT1 →	+0.236	+0.310	<.001	<.001	3	8
BRCA	SRRM2 →	+0.240	+0.237	<.001	<.001	3	8
COAD	ATXN2L →	+0.218	+0.324	<.001	<.001	3	7
GBM	G3BP1 →	+0.198	+0.108	<.001	<.001	3	7
LUAD	NOL6 →	+0.274	+0.223	<.001	<.001	3	7
HNSC	PABPC1 →	+0.265	+0.246	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,890 associations by consensus.

ZNF598 vs GSPT1 — COAD

Explore this scatter interactively →