ZNF598

Across TCGA patient cohorts, ZNF598 mutation is significantly associated with the RNA expression of many other genes, with 1,160 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF598-associated genes across cancer lineages are RPS29P32, RN7SKP79, and RNU6-960P. Each is linked with ZNF598 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF598-to-partner and partner-to-ZNF598 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by ZNF598-low versus ZNF598-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF598→partner) and Y-score (partner→ZNF598) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS29P32 →	+0.510	+5.649	<.001	.001	3	2
COAD	RN7SKP79 →	+0.795	+4.080	<.001	.002	3	2
COAD	RNU6-960P →	+1.177	+4.251	<.001	.008	3	2
COAD	RNU6-522P →	+0.876	+4.392	<.001	.006	3	2
COAD	RNY1P2 →	+0.228	+5.734	<.001	<.001	3	2
COAD	RNU6-142P →	+0.882	+4.547	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,160 associations by consensus.

RPS29P32 by ZNF598 expression — BRCA

Explore this box plot interactively →