ZNF595

Across TCGA cell cohorts, ZNF595 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,203 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF595-associated GO terms across cancer lineages are Regulation of lymphocyte migration, Negative regulation of adaptive immune response, and Negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Each is linked with ZNF595 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF595-to-partner and partner-to-ZNF595 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lymphocyte migration grouped by ZNF595-low versus ZNF595-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF595→partner) and Y-score (partner→ZNF595) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of lymphocyte migration →	-0.073	-1.654	.001	.001	3	11
BLOOD_Lymphoma	Negative regulation of adaptive immune response →	-0.067	-2.058	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	-0.061	-2.361	.003	.003	3	9
LUNG_NSCLC_LUSC	Gamma-aminobutyric acid signaling pathway →	-0.225	-2.738	<.001	<.001	3	9
BONE	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.113	+1.310	.004	.002	3	9
LUNG_NSCLC_LUSC	Positive regulation of lymphocyte migration →	-0.138	-3.327	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,203 associations by consensus.

Regulation of lymphocyte migration by ZNF595 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →