ZNF595

Across TCGA cell cohorts, ZNF595 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF595-associated genes across cancer lineages are AKAP4, CLEC4C, and RFPL3. Each is linked with ZNF595 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF595-to-partner and partner-to-ZNF595 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKAP4 grouped by ZNF595-low versus ZNF595-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF595→partner) and Y-score (partner→ZNF595) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	AKAP4 →	+0.012	+3.232	.001	.008	3	1
SKIN	CLEC4C →	+0.050	+4.977	<.001	.007	3	1
LARGE_INTESTINE	RFPL3 →	+0.027	+2.925	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

AKAP4 by ZNF595 expression — LUNG_SCLC

Explore this box plot interactively →