ZNF593

Across TCGA pan-cancer cohorts, ZNF593 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ZNF593’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ZNF593 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF593 is over-expressed in tumor.

COAD, LUAD, and LSCC are the cancer types where ZNF593 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF593 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	+0.482	<.001	9	view →
LUAD	All	All	+0.174	<.001	4	view →
LSCC	Female	All	+0.156	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ZNF593–COAD

Open the COAD breakdown →