ZNF592

Across TCGA patient cohorts, ZNF592 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,340 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF592-associated proteins across cancer lineages are CTDSPL2, ZNF592_S348, and SIN3A. Each is linked with ZNF592 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF592-to-partner and partner-to-ZNF592 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF592 versus CTDSPL2 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF592→partner) and Y-score (partner→ZNF592) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CTDSPL2 →	+0.418	+0.295	<.001	<.001	3	9
LSCC	ZNF592_S348 →	+0.468	+0.276	<.001	<.001	3	8
GBM	SIN3A →	+0.364	+0.317	<.001	<.001	3	8
BRCA	ZNF592_S331 →	+0.594	+0.256	<.001	<.001	3	7
LUAD	ANP32A →	+0.371	+0.252	<.001	<.001	3	7
GBM	PDS5B →	+0.248	+0.210	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,340 associations by consensus.

ZNF592 vs CTDSPL2 — BRCA

Explore this scatter interactively →