ZNF592

Across TCGA patient cohorts, ZNF592 mutation is significantly associated with the RNA expression of many other genes, with 3,676 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF592-associated genes across cancer lineages are C15orf61, H3P26, and MIRLET7BHG. Each is linked with ZNF592 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF592-to-partner and partner-to-ZNF592 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C15orf61 grouped by ZNF592-low versus ZNF592-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF592→partner) and Y-score (partner→ZNF592) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C15orf61 →	+0.349	+2.807	<.001	<.001	3	5
LIHC	H3P26 →	+0.186	+4.776	<.001	.003	3	3
COAD	MIRLET7BHG →	+0.952	+3.348	<.001	.005	3	3
LUAD	UBE2SP1 →	+0.732	+3.333	.001	.005	2	4
COAD	OTX1 →	+0.913	+3.348	<.001	.005	3	3
UCEC	PSMB2 →	+0.304	+1.868	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,676 associations by consensus.

C15orf61 by ZNF592 expression — UCEC

Explore this box plot interactively →