ZNF589

Across TCGA cell cohorts, ZNF589 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF589-associated genes across cancer lineages are ARL13A, TBC1D3, and FAM205A. Each is linked with ZNF589 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF589-to-partner and partner-to-ZNF589 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARL13A grouped by ZNF589-low versus ZNF589-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF589→partner) and Y-score (partner→ZNF589) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARL13A →	+0.071	+3.632	<.001	.003	3	1
LARGE_INTESTINE	TBC1D3 →	+0.044	+2.688	.005	.008	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.029	<.001	.002	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ARL13A by ZNF589 expression — LARGE_INTESTINE

Explore this box plot interactively →