ZNF587B

Across TCGA cell cohorts, ZNF587B mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF587B-associated genes across cancer lineages are TRIM42, WFDC10B, and AADACL3. Each is linked with ZNF587B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF587B-to-partner and partner-to-ZNF587B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM42 grouped by ZNF587B-low versus ZNF587B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF587B→partner) and Y-score (partner→ZNF587B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TRIM42 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	WFDC10B →	+0.063	+4.922	<.001	.009	3	1
BLOOD_Leukemia	AADACL3 →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	OC90 →	+0.006	+5.201	.003	.006	3	1
BLOOD_Leukemia	OR1D4 →	+0.031	+5.539	.001	.003	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TRIM42 by ZNF587B expression — BLOOD_Leukemia

Explore this box plot interactively →