Across TCGA cell cohorts, ZNF587 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF587-associated genes across cancer lineages are SULT6B1, XCL2, and GRID2. Each is linked with ZNF587 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF587-to-partner and partner-to-ZNF587 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF587→partner) and Y-score (partner→ZNF587) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SULT6B1 →	+0.024	+3.240	<.001	.004	3	1
LARGE_INTESTINE	XCL2 →	+0.071	+3.084	.001	.002	3	1
LARGE_INTESTINE	GRID2 →	+0.024	+3.777	<.001	.001	3	1
LARGE_INTESTINE	WNT9B →	+0.036	+2.688	<.001	.008	3	1
LARGE_INTESTINE	GPR148 →	+0.058	+2.882	<.001	.005	3	1
LARGE_INTESTINE	PIWIL3 →	+0.029	+2.791	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ZNF587 survival (RNA) · tumor vs normal (RNA) · all ZNF587 data types