ZNF586

Across TCGA patient cohorts, ZNF586 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,640 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF586-associated proteins across cancer lineages are TRIM28, RO60, and CHMP2A. Each is linked with ZNF586 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF586-to-partner and partner-to-ZNF586 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF586 versus TRIM28 in GBM, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF586→partner) and Y-score (partner→ZNF586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.467	+0.562	<.001	<.001	3	6
BRCA	RO60 →	+0.219	+0.591	<.001	<.001	3	4
BRCA	CHMP2A →	+0.430	+0.792	<.001	<.001	3	4
OV	UBE2M →	+0.322	+0.804	<.001	.002	3	4
BRCA	TBRG4 →	-0.422	-0.865	<.001	<.001	3	4
BRCA	ZNF219_S698 →	+0.792	+0.989	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,640 associations by consensus.

ZNF586 vs TRIM28 — GBM

Explore this scatter interactively →