ZNF586

Across TCGA patient cohorts, ZNF586 protein abundance is significantly associated with the RNA expression of many other genes, with 695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF586-associated genes across cancer lineages are OR2I1P, ETV7, and MSLN. Each is linked with ZNF586 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF586-to-partner and partner-to-ZNF586 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF586 versus OR2I1P in COAD, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF586→partner) and Y-score (partner→ZNF586) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR2I1P →	+3.008	+1.241	.003	.002	3	2
COAD	ETV7 →	+2.383	+1.405	<.001	<.001	3	1
COAD	MSLN →	-2.831	-1.012	<.001	.001	3	1
COAD	SLC7A6OS →	+0.571	+1.248	<.001	<.001	3	1
COAD	EARS2 →	+0.746	+1.245	<.001	<.001	3	1
COAD	IL7 →	+0.943	+0.983	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 695 associations by consensus.

ZNF586 vs OR2I1P — COAD

Explore this scatter interactively →