Across TCGA patient cohorts, ZNF585A mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF585A-associated genes across cancer lineages are ASNS, eIF4E, and PCNA. Each is linked with ZNF585A in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF585A-to-partner and partner-to-ZNF585A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF585A→partner) and Y-score (partner→ZNF585A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.418	+1.247	<.001	.041	3	4
UCEC	eIF4E →	+0.184	+2.321	.003	<.001	3	3
UCEC	PCNA →	+0.164	+1.736	.010	.006	3	3
SKCM	Stathmin →	+0.132	+3.321	.043	.009	3	3
UCEC	GAPDH →	+0.378	+1.584	.018	.032	3	2
UCEC	STAT3_pY705 →	-0.266	-1.382	<.001	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

ZNF585A survival (RNA) · tumor vs normal (RNA) · all ZNF585A data types