ZNF584

Across TCGA patient cohorts, ZNF584 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,791 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF584-associated proteins across cancer lineages are TRIM28, RUVBL2, and SAE1. Each is linked with ZNF584 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF584-to-partner and partner-to-ZNF584 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF584 versus TRIM28 in GBM, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF584→partner) and Y-score (partner→ZNF584) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.393	+0.509	<.001	<.001	3	7
LSCC	RUVBL2 →	+0.372	+0.546	<.001	<.001	3	5
GBM	SAE1 →	+0.316	+0.378	<.001	<.001	3	5
BRCA	ISG20 →	-0.510	-0.354	.001	.002	3	5
GBM	CASP4 →	-0.559	-0.429	<.001	<.001	2	6
CCRCC	CCDC88B →	-0.467	-0.257	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,791 associations by consensus.

ZNF584 vs TRIM28 — GBM

Explore this scatter interactively →