ZNF584

Across TCGA patient cohorts, ZNF584 protein abundance is significantly associated with the RNA expression of many other genes, with 448 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF584-associated genes across cancer lineages are SMURF2, AICDA, and ZNF706. Each is linked with ZNF584 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF584-to-partner and partner-to-ZNF584 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF584 versus SMURF2 in BRCA, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF584→partner) and Y-score (partner→ZNF584) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SMURF2 →	+0.812	+0.785	.002	.008	3	1
BRCA	AICDA →	+0.091	+0.801	<.001	<.001	3	1
BRCA	ZNF706 →	+0.770	+0.775	.009	.004	3	1
BRCA	GGA3 →	+0.600	+0.580	.007	.008	3	1
BRCA	NUP85 →	+0.908	+0.960	<.001	.005	3	1
BRCA	DAGLA →	+1.360	+0.835	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 448 associations by consensus.

ZNF584 vs SMURF2 — BRCA

Explore this scatter interactively →