ZNF584

Across TCGA patient cohorts, ZNF584 mutation is significantly associated with the RNA expression of many other genes, with 2,835 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF584-associated genes across cancer lineages are RNU6-1213P, RNU6-756P, and MIR6894. Each is linked with ZNF584 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF584-to-partner and partner-to-ZNF584 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by ZNF584-low versus ZNF584-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF584→partner) and Y-score (partner→ZNF584) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.280	+4.176	<.001	<.001	3	3
BLCA	RNU6-756P →	+0.333	+7.640	<.001	.009	3	2
UCEC	MIR6894 →	+0.522	+1.981	.002	.007	3	2
UCEC	TWF1 →	+0.748	+3.346	.002	.005	3	2
UCEC	PELO →	+0.512	+3.483	.002	.002	3	2
UCEC	HS2ST1 →	+0.548	+3.467	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,835 associations by consensus.

RNU6-1213P by ZNF584 expression — UCEC

Explore this box plot interactively →