ZNF584

Across TCGA cell cohorts, ZNF584 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF584-associated genes across cancer lineages are OR51T1, GSG1L2, and GALR3. Each is linked with ZNF584 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF584-to-partner and partner-to-ZNF584 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by ZNF584-low versus ZNF584-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF584→partner) and Y-score (partner→ZNF584) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	GALR3 →	+0.148	+3.646	<.001	.002	3	1
LARGE_INTESTINE	CPO →	+0.121	+3.514	<.001	.007	3	1
LARGE_INTESTINE	RBMXL2 →	+0.062	+2.817	.003	.007	3	1
LARGE_INTESTINE	WDR87 →	+0.023	+3.353	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR51T1 by ZNF584 expression — BLOOD_Leukemia

Explore this box plot interactively →