ZNF582

Across TCGA patient cohorts, ZNF582 protein abundance is significantly associated with the RNA expression of many other genes, with 530 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF582-associated genes across cancer lineages are TRIM35, LYL1, and ASPN. Each is linked with ZNF582 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF582-to-partner and partner-to-ZNF582 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF582 versus TRIM35 in GBM, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF582→partner) and Y-score (partner→ZNF582) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM35 →	+0.429	+0.849	.005	.002	3	1
GBM	LYL1 →	+0.843	+0.584	.005	.007	3	1
GBM	ASPN →	-0.897	-0.597	.001	<.001	3	1
GBM	SUFU →	+0.483	+0.571	.003	<.001	3	1
GBM	STN1 →	+0.716	+0.878	.001	<.001	3	1
GBM	PBLD →	+0.424	+0.791	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

ZNF582 vs TRIM35 — GBM

Explore this scatter interactively →