ZNF582

Across TCGA patient cohorts, ZNF582 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,030 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF582-associated proteins across cancer lineages are APC_S2283, BRD4, and BRD7_S621. Each is linked with ZNF582 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF582-to-partner and partner-to-ZNF582 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF582 versus APC_S2283 in PDAC, with a Pearson correlation of -0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF582→partner) and Y-score (partner→ZNF582) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	APC_S2283 →	-0.815	-0.531	.001	<.001	3	1
PDAC	BRD4 →	-0.263	-0.715	.002	<.001	3	1
PDAC	BRD7_S621 →	-0.577	-0.683	<.001	<.001	3	1
PDAC	ADAMTS4 →	+1.312	+0.774	<.001	.001	3	1
PDAC	BST1 →	+1.141	+0.727	<.001	<.001	3	1
PDAC	C1orf226_S249 →	-0.927	-0.532	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,030 associations by consensus.

ZNF582 vs APC_S2283 — PDAC

Explore this scatter interactively →