ZNF582

Across TCGA patient cohorts, ZNF582 mutation is significantly associated with the RNA expression of many other genes, with 2,654 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF582-associated genes across cancer lineages are FAM47A, MIR548T, and TRPC7-AS1. Each is linked with ZNF582 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF582-to-partner and partner-to-ZNF582 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by ZNF582-low versus ZNF582-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF582→partner) and Y-score (partner→ZNF582) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	FAM47A →	+0.018	+4.306	<.001	.001	3	3
READ	MIR548T →	+0.862	+5.653	<.001	.003	3	3
LUSC	TRPC7-AS1 →	+0.262	+4.494	.004	<.001	3	3
SKCM	POU5F1P5 →	+0.045	+2.032	.005	.003	3	3
UCEC	HMGCS1 →	+0.555	+2.526	.006	.001	3	3
UCEC	RNFT2 →	+0.524	+2.928	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,654 associations by consensus.

FAM47A by ZNF582 expression — CESC

Explore this box plot interactively →