ZNF582

Across TCGA cell cohorts, ZNF582 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,784 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF582-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with ZNF582 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF582-to-partner and partner-to-ZNF582 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by ZNF582-low versus ZNF582-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF582→partner) and Y-score (partner→ZNF582) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.097	+1.046	<.001	.002	3	10
BREAST	Negative regulation of myoblast fusion →	+0.082	+0.933	<.001	<.001	3	9
BREAST	Cytoplasmic translation →	+0.081	+1.107	<.001	<.001	3	9
BONE	Regulation of myoblast fusion →	+0.099	+1.509	<.001	<.001	2	9
PANCREAS	Potassium ion transport →	-0.062	-0.701	<.001	<.001	3	8
SKIN	Potassium ion transmembrane transport →	-0.061	-1.242	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,784 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by ZNF582 expression — BREAST

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