ZNF582-AS1

Across TCGA pan-cancer cohorts, ZNF582-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF582-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ZNF582-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF582-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and KIRC show a favorable association.

UVM, KIRC, and UCS are the cancer types where ZNF582-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.789	0.372	<.001	98	view →
KIRC	DFS	Median	All	0.699	0.558	<.001	41	view →
UCS	DFS	Tertile	III,IV	0.583	0.141	<.001	36	view →
LGG	DFS	Median	All	0.664	0.805	<.001	35	view →
CESC	OS	Median	IV	0.668	0.086	<.001	34	view →
PAAD	DFS	Quartile	All	0.573	0.187	<.001	33	view →
UCEC	OS	Tertile	All	0.735	0.477	.011	30	view →
LUAD	OS	Median	All	0.738	0.630	.003	26	view →
MESO	OS	Median	All	0.672	0.344	.028	15	view →
KIRP	DFS	Quartile	All	0.949	0.821	.010	14	view →
ACC	DFS	Tertile	IV	0.777	0.212	.024	12	view →
LIHC	OS	Tertile	All	0.787	0.386	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF582-AS1–UVM (OS)

Open the UVM breakdown →