Across TCGA patient cohorts, ZNF580 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF580-associated genes across cancer lineages are LINC02726, DHFRP3, and FAM71BP1. Each is linked with ZNF580 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF580-to-partner and partner-to-ZNF580 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF580→partner) and Y-score (partner→ZNF580) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02726 →	+0.352	+5.133	<.001	.008	3	2
BLCA	DHFRP3 →	+0.103	+5.329	.008	.006	3	1
UCEC	FAM71BP1 →	+0.338	+6.335	<.001	.001	3	1
UCEC	FRG2MP →	+0.281	+5.031	<.001	.009	3	1
UCEC	RN7SL457P →	+0.350	+4.982	.003	.009	3	1
UCEC	GRAMD4P7 →	+0.199	+5.081	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

ZNF580 survival (RNA) · tumor vs normal (RNA) · all ZNF580 data types