ZNF574

Across TCGA patient cohorts, ZNF574 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,438 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF574-associated proteins across cancer lineages are XRCC1, SRRT, and TRIM28. Each is linked with ZNF574 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF574-to-partner and partner-to-ZNF574 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF574 versus XRCC1 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF574→partner) and Y-score (partner→ZNF574) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XRCC1 →	+0.437	+0.608	<.001	<.001	3	6
GBM	SRRT →	+0.253	+0.316	.001	.005	3	6
GBM	TRIM28 →	+0.431	+0.403	<.001	<.001	3	6
OV	PAFAH1B3 →	+0.526	+0.713	.002	.003	3	6
LSCC	IRF2BP1 →	+0.412	+0.526	<.001	<.001	3	6
GBM	HNRNPUL1 →	+0.339	+0.376	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,438 associations by consensus.

ZNF574 vs XRCC1 — LSCC

Explore this scatter interactively →