Across TCGA cell cohorts, ZNF573 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF573-associated genes across cancer lineages are HHLA1, KRTAP21-2, and CABP5. Each is linked with ZNF573 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF573-to-partner and partner-to-ZNF573 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF573→partner) and Y-score (partner→ZNF573) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	KRTAP21-2 →	+0.115	+4.539	<.001	.007	3	1
LUNG_NSCLC_LUAD	CABP5 →	+0.273	+3.481	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR2B11 →	+0.132	+3.215	<.001	.007	3	1
LUNG_NSCLC_LUAD	TEX33 →	+0.018	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	MBD3L4 →	+0.011	+4.266	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

ZNF573 survival (RNA) · tumor vs normal (RNA) · all ZNF573 data types