ZNF572

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF572 mutation is significantly associated with the RNA expression of many other genes, with 1,824 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF572-associated genes across cancer lineages are TAF9, TRIM36, and NDUFS5. Each is linked with ZNF572 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF572-to-partner and partner-to-ZNF572 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by ZNF572-low versus ZNF572-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF572→partner) and Y-score (partner→ZNF572) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTAF9 →+0.609+2.928<.001<.00133
UCECTRIM36 →+0.710+2.201<.001<.00133
UCECNDUFS5 →+0.446+3.711<.001<.00133
UCECEIF2B2 →+0.428+2.364<.001.00233
UCECZCCHC17 →+0.316+1.949.001.00133
UCECIMP3 →+0.296+2.279.003.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,824 associations by consensus.

TAF9 by ZNF572 expression — UCEC

Box plot of TAF9 in ZNF572-low vs ZNF572-high samples in UCEC.

Explore this box plot interactively →

Exploration