ZNF571

Across TCGA patient cohorts, ZNF571 mutation is significantly associated with the RNA expression of many other genes, with 2,664 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF571-associated genes across cancer lineages are CYCSP19, YWHAZP1, and PSAT1P4. Each is linked with ZNF571 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF571-to-partner and partner-to-ZNF571 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYCSP19 grouped by ZNF571-low versus ZNF571-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF571→partner) and Y-score (partner→ZNF571) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYCSP19 →	+0.136	+1.528	<.001	.007	3	2
BRCA	YWHAZP1 →	+0.109	+5.347	<.001	.006	3	2
UCEC	PSAT1P4 →	+0.137	+1.863	<.001	<.001	3	2
UCEC	EZH2P1 →	+0.251	+1.666	.001	.001	3	2
LUAD	BNIP3P6 →	+1.070	+4.399	<.001	.006	3	2
BLCA	NTF6A →	+0.249	+5.177	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,664 associations by consensus.

CYCSP19 by ZNF571 expression — UCEC

Explore this box plot interactively →