ZNF571-AS1

Across TCGA pan-cancer cohorts, ZNF571-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZNF571-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ZNF571-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF571-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and BLCA show a favorable association.

UVM, BLCA, and KIRC are the cancer types where ZNF571-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.803	0.373	<.001	97	view →
BLCA	OS	Median	All	0.672	0.539	<.001	64	view →
KIRC	DFS	Tertile	All	0.542	0.688	.004	57	view →
LUAD	OS	Tertile	All	0.889	0.688	<.001	46	view →
PAAD	DFS	Tertile	All	0.588	0.346	<.001	45	view →
UCEC	OS	Tertile	All	0.843	0.914	.012	44	view →
ACC	DFS	Tertile	All	0.244	0.717	.003	35	view →
HNSC	DFS	Median	IV	0.454	0.281	.005	18	view →
UCS	OS	Median	II,III,IV	0.741	0.445	.016	18	view →
LGG	OS	Tertile	All	0.934	0.823	<.001	18	view →
BRCA	OS	Tertile	II,III,IV	0.971	0.932	.010	16	view →
GBM	DFS	Quartile	All	0.452	0.165	.004	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZNF571-AS1–UVM (OS)

Open the UVM breakdown →