ZNF571-AS1

Across TCGA pan-cancer cohorts, ZNF571-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ZNF571-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ZNF571-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF571-AS1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and THCA are the cancer types where ZNF571-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF571-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	−0.393	<.001	11	view →
KICH	Male	All	−0.433	<.001	8	view →
THCA	Female	All	+0.704	<.001	6	view →
READ	All	II,III,IV	−0.392	.001	5	view →
LIHC	All	All	+0.120	.001	4	view →
CHOL	All	II,III,IV	+0.420	.009	3	view →
PRAD	All	All	+0.424	<.001	2	view →
LUAD	All	All	+0.340	<.001	2	view →
BLCA	Female	IV	+0.209	.004	1	view →
HNSC	Female	IV	−0.163	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ZNF571-AS1–COAD

Open the COAD breakdown →