ZNF570

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF570 protein abundance is significantly associated with the RNA expression of many other genes, with 232 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF570-associated genes across cancer lineages are LYRM1, CFAP92, and HELLS. Each is linked with ZNF570 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF570-to-partner and partner-to-ZNF570 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF570 versus LYRM1 in BRCA, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF570→partner) and Y-score (partner→ZNF570) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALYRM1 →+0.594+0.505<.001.00231
BRCACFAP92 →+1.754+0.425.003.00331
BRCAHELLS →+0.475+0.325.005.00931
BRCAEMC1 →+0.860+0.325.001.00931
BRCAKCNC3 →-1.970-0.325.008.00931
BRCATMTC1 →+0.787+0.325<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 232 associations by consensus.

ZNF570 vs LYRM1 — BRCA

Per-sample scatter of ZNF570 vs LYRM1 in BRCA (Pearson r = 0.92).

Explore this scatter interactively →

Exploration