ZNF57

Across TCGA patient cohorts, ZNF57 mutation is significantly associated with the RNA expression of many other genes, with 3,174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF57-associated genes across cancer lineages are TRMT112P1, LIMS4, and ATP5PBP7. Each is linked with ZNF57 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF57-to-partner and partner-to-ZNF57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMT112P1 grouped by ZNF57-low versus ZNF57-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF57→partner) and Y-score (partner→ZNF57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TRMT112P1 →	+0.181	+4.282	<.001	.009	3	3
SKCM	LIMS4 →	+0.027	+5.408	<.001	.002	3	2
SKCM	ATP5PBP7 →	+0.077	+4.072	.002	.005	3	2
UCEC	TRAJ57 →	+0.354	+2.038	<.001	.003	3	2
UCEC	PINCR →	+0.144	+1.633	.003	.006	3	2
UCEC	RNA5SP411 →	+1.121	+2.152	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,174 associations by consensus.

TRMT112P1 by ZNF57 expression — SKCM

Explore this box plot interactively →